Journal article

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

Kate E Mackin, Briony Elliott, Despina Kotsanas, Benjamin P Howden, Glen P Carter, Tony M Korman, Thomas V Riley, Julian I Rood, Grant A Jenkin, Dena Lyras

ANAEROBE | ELSEVIER SCI LTD | Published : 2015

Abstract

Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.

Grants

Awarded by Australian National Health and Medical Research Council (NHMRC)


Awarded by Australian Research Council (ARC)


Awarded by ARC Future Fellowship


Awarded by NHMRC Career Development Fellowship


Funding Acknowledgements

The researchers were supported by Project Grant GNT1051584 from the Australian National Health and Medical Research Council (NHMRC) and Discovery Grant DP1093891 from the Australian Research Council (ARC). DL was supported by an ARC Future Fellowship (FT120100779) from the ARC. BH was supported by an NHMRC Career Development Fellowship (GNT1023526).