Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

KE Mackin; B Elliott; D Kotsanas; BP Howden; GP Carter; TM Korman; TV Riley; JI Rood; GA Jenkin; D Lyras

Journal article

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia

KE Mackin, B Elliott, D Kotsanas, BP Howden, GP Carter, TM Korman, TV Riley, JI Rood, GA Jenkin, D Lyras

Anaerobe | ELSEVIER SCI LTD | Published : 2015

DOI: 10.1016/j.anaerobe.2015.05.001

Abstract

Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.

University of Melbourne Researchers

Ben Howden Author

Glen Carter Author

Related Projects (1)

UNDERSTANDING AND COMBATING BACTERIAL INFECTIONS

This project will focus on two important bacteria, Staphylococcus aureus (Golden Staph), and Enterococcus faecium, both causes of serious in..

Grants

Awarded by Australian Research Council

Funding Acknowledgements

The researchers were supported by Project Grant GNT1051584 from the Australian National Health and Medical Research Council (NHMRC) and Discovery Grant DP1093891 from the Australian Research Council (ARC). DL was supported by an ARC Future Fellowship (FT120100779) from the ARC. BH was supported by an NHMRC Career Development Fellowship (GNT1023526).