Journal article

Preterm or Not - An Evaluation of Estimates of Gestational Age in a Cohort of Women from Rural Papua New Guinea

Stephan Karl, Connie SN Li Wai Suen, Holger W Unger, Maria Ome-Kaius, Glen Mola, Lisa White, Regina A Wangnapi, Stephen J Rogerson, Ivo Mueller



BACKGROUND: Knowledge of accurate gestational age is required for comprehensive pregnancy care and is an essential component of research evaluating causes of preterm birth. In industrialised countries gestational age is determined with the help of fetal biometry in early pregnancy. Lack of ultrasound and late presentation to antenatal clinic limits this practice in low-resource settings. Instead, clinical estimators of gestational age are used, but their accuracy remains a matter of debate. METHODS: In a cohort of 688 singleton pregnancies from rural Papua New Guinea, delivery gestational age was calculated from Ballard score, last menstrual period, symphysis-pubis fundal height at first vis..

View full abstract


Awarded by Malaria in Pregnancy Consortium (Bill & Melinda Gates Foundation)

Awarded by Pfizer Inc

Awarded by Pregvax Consortium from the European Union

Awarded by NHMRC early career fellowship

Awarded by NHMRC Senior Research Fellowship

Funding Acknowledgements

This research was supported by the Malaria in Pregnancy Consortium (Bill & Melinda Gates Foundation grant number 46099); Pfizer Inc (investigator initiated research grant WS394663); a PNGIMR Internal Competitive Research Award to MO, and the Pregvax Consortium, through a grant from the European Union's Seventh Framework Programme FP7-2007-HEALTH (PREGVAX 201588) SK is supported through an NHMRC early career fellowship (#1052960), and IM received an NHMRC Senior Research Fellowship (#1043345). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.