Journal article

A Comprehensive Atlas of the Adult Mouse Penis

A PASK, TR Phillips, DK Wright, PE Gradie, LA Johnston

SEXUAL DEVELOPMENT | Karger | Published : 2015

Abstract

Mice are routinely used to study the development of the external genitalia and, in particular, the process of male urethral closure. This is because misplacement of the male penile urethra, or hypospadias, is amongst the most common birth defects reported in humans. While mice present a tractable model to study penile development, several structures differ between mice and humans and there is a lack of consensus in the literature on their annotation and developmental origins. Defining the ontology of the mouse prepuce is especially important for the relevance and interpretation of mouse models of hypospadias to human conditions. We have developed a detailed annotation of the adult mouse peni..

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Grants

Awarded by National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health


Funding Acknowledgements

The authors acknowledge the facilities and the scientific and technical assistance of the National Imaging Facility at the Florey Institute of Neuroscience and Mental Health, Parkville. Research reported in this publication was supported by The National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health under award number R01DK096263.