Journal article

EARLY HIV-RELATED NEUROPSYCHOLOGICAL IMPAIRMENT - RELATIONSHIP TO STAGE OF VIRAL-INFECTION

A GIBBS, G SZMUKLER, DG ANDREWES, B MULHALL, SC BOWDEN

JOURNAL OF CLINICAL AND EXPERIMENTAL NEUROPSYCHOLOGY | SWETS ZEITLINGER PUBLISHERS | Published : 1990

Abstract

Sixty male outpatients with no past neuropsychiatric history were examined for evidence of early HIV-related neuropsychological impairment. Significant cognitive deficit, as measured by the RAVLT and WAIS-R Digit Symbol Substitution tests, and moderate correlation with indices of immune function, were observed in a group of patients with AIDS-Related Complex [ARC]. Patients with asymptomatic HIV-infection demonstrated no significant differences in performance compared to a group of HIV-seronegative controls. No significant group differences in age, education, predicted-IQ or self-rated depression and anxiety were observed. These results support the hypothesis that HIV-related cognitive distu..

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