Journal article

Multimodality MRI in mesial temporal sclerosis: Relative sensitivity and specificity

RI Kuzniecky, E Bilir, F Gilliam, E Faught, C Palmer, R Morawetz, G Jackson

Neurology | LIPPINCOTT-RAVEN PUBL | Published : 1997


Our objectives were to determine the relative sensitivity and specificity of different MRI sequences and analysis techniques for the detection of mesial temporal sclerosis (MTS). Mesial temporal sclerosis is the most common pathologic finding in patients undergoing temporal lobe epilepsy surgery. Magnetic resonance imaging is the most reliable preoperative imaging technique for the detection of MTS. We analyzed the abnormalities in preoperative MRIs of 44 consecutive patients who had undergone temporal lobectomy and who had pathologic confirmation of MTS. Techniques included inversion recovery (IR); T1-weighted, volume-acquired images; hippocampal T2 relaxometry (HT2); volumetric assessment;..

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