Journal article

OPTIMIZING THE DIAGNOSIS OF HIPPOCAMPAL SCLEROSIS USING MR-IMAGING

GD JACKSON, SF BERKOVIC, JS DUNCAN, A CONNELLY

American Journal of Neuroradiology | AMER SOC NEURORADIOLOGY | Published : 1993

Abstract

PURPOSE: To establish the optimal imaging parameters and MR features of hippocampal sclerosis. METHODS: Twenty-five outpatients with intractable temporal lobe epilepsy and 10 control subjects were studied at 1.5T. Four features of hippocampal abnormality were specifically evaluated; increased hippocampal signal on T2-weighted images, decreased signal on T1-weighted images, hippocampal atrophy, and disruption of the internal hippocampal structure. RESULTS: Hippocampal sclerosis was diagnosed alone in 64% of patients and with ipsilateral pathology in a further 8%. In these 18 cases, increased hippocampal signal on T2-weighted images was seen in 77%, hippocampal atrophy in 83%, decreases signal..

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