Functional Bimodality in the Brain Networks of Preterm and Term Human Newborns
Amir Omidvarnia, Peter Fransson, Marjo Metsaranta, Sampsa Vanhatalo
CEREBRAL CORTEX | OXFORD UNIV PRESS INC | Published : 2014
The spontaneous brain activity exhibits long-range spatial correlations detected using functional magnetic resonance imaging (fMRI) signals in newborns when (1) long neuronal pathways are still developing, and (2) the electrical brain activity consists of developmentally unique, intermittent events believed to guide activity-dependent brain wiring. We studied this spontaneous electrical brain activity using multichannel electroencephalography (EEG) of premature and fullterm babies during sleep to assess the development of spatial integration during last months of gestation. Correlations of frequency-specific amplitudes were found to follow a robust bimodality: During low amplitudes (low mode..View full abstract
Awarded by European Community
This work was supported by Helsinki University Hospital and Juselius Foundation. S. V. received support from the European Community's Seventh Framework Programme (FP7-PEOPLE-2009-IOF, grant agreement no. 254235), P. F. was supported by the Swedish Research Agency, and A.O. received financial support from the Perinatal Research Centre of Prof. Paul Colditz, UQCCR.