Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)

Ora Paltiel; Gabriella Tikellis; Martha Linet; Jean Golding; Stanley Lemeshow; Gary Phillips; Karen Lamb; Camilla Stoltenberg; Siri E Haberg; Marin Strom; Charlotta Granstrom; Kate Northstone; Mark Klebanoff; Anne-Louise Ponsonby; Elizabeth Milne; Marie Pedersen; Manolis Kogevinas; Eunhee Ha; Terence Dwyer

Journal article

Birthweight and Childhood Cancer: Preliminary Findings from the International Childhood Cancer Cohort Consortium (I4C)

Ora Paltiel, Gabriella Tikellis, Martha Linet, Jean Golding, Stanley Lemeshow, Gary Phillips, Karen Lamb, Camilla Stoltenberg, Siri E Haberg, Marin Strom, Charlotta Granstrom, Kate Northstone, Mark Klebanoff, Anne-Louise Ponsonby, Elizabeth Milne, Marie Pedersen, Manolis Kogevinas, Eunhee Ha, Terence Dwyer

Paediatric and Perinatal Epidemiology | WILEY-BLACKWELL | Published : 2015

DOI: 10.1111/ppe.12193

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Abstract

BACKGROUND: Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies. We aimed to investigate this association, exploring the potential modifying roles of age at diagnosis and maternal anthropometrics, using prospectively collected data from the International Childhood Cancer Cohort Consortium. METHODS: We pooled data on infant and parental characteristics and cancer incidence from six geographically and temporally diverse member cohorts [the Avon Longitudinal Study of Parents and Children (UK), the Collaborative Perinatal Project (USA), the Danish National Birth Cohort (Denmark), the Jerusalem Perinatal Study (Israel), the Norwegian ..

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University of Melbourne Researchers

Karen Lamb Author Melbourne School of Population and Global Health

Anne-Louise Ponsonby Author Melbourne School of Population and Global Health

Terry Dwyer Author Paediatrics Royal Children's Hospital

Grants

Awarded by Murdoch Children's Research Institution, Australia

Awarded by Wellcome Trust

Awarded by Medical Research Council

Awarded by NATIONAL CANCER INSTITUTE

Funding Acknowledgements

This work was supported by: NIH (NCI, NICHD) USA; National Children's Study - USA; the Childrens Cancer Centre Foundation - Australia; Bluey Day Foundation - Australia; Baxter Family Foundation - Australia; The Rotary Club of North Brighton - Australia; Tour de Cure - Australia; Private philanthropic donations - Australia; and Murdoch Children's Research Institution (M1300049), Australia. The UK Medical Research Council and the Wellcome Trust (Grant ref: 092731) and the University of Bristol provide core support for ALSPAC. The Maria Ascoli Foundation, Jerusalem, Israel, provided support for data pooling of the JPS.