Journal article
Crowdsourcing the General Public for Large Scale Molecular Pathology Studies in Cancer
FJ Candido dos Reis, S Lynn, HR Ali, D Eccles, A Hanby, E Provenzano, C Caldas, WJ Howat, LA McDuffus, B Liu, F Daley, P Coulson, RJ Vyas, LM Harris, JM Owens, AFM Carton, JP McQuillan, AM Paterson, Z Hirji, SK Christie Show all
Ebiomedicine | ELSEVIER SCIENCE BV | Published : 2015
Open access
Abstract
Background: Citizen science, scientific research conducted by non-specialists, has the potential to facilitate biomedical research using available large-scale data, however validating the results is challenging. The Cell Slider is a citizen science project that intends to share images from tumors with the general public, enabling them to score tumor markers independently through an internet-based interface. Methods: From October 2012 to June 2014, 98,293 Citizen Scientists accessed the Cell Slider web page and scored 180,172 sub-images derived from images of 12,326 tissue microarray cores labeled for estrogen receptor (ER). We evaluated the accuracy of Citizen Scientist's ER classification, ..
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Awarded by National Institutes of Health
Funding Acknowledgements
Cell Slider is supported by funding from Cancer Research UK. The individual studies were supported by grants from: Cancer Research UK (C490/A10124, C490/A16561), Dutch Cancer Society (NKI 2007-3839 and 2009-4363), the NIHR Biomedical Research Centre at the University of Cambridge, Yorkshire Cancer Research (S295, S299, S305PA), Red Tematica de Investigacion Cooperativa en Cancer, Fondo de Investigacion Sanitario (PI11/00923 and PI081120). The Human Genotyping-CEGEN Unit (CNIO) is supported by the Instituto de Salud Carlos III and the ESTHER study was supported by the Baden Wurttemberg Ministry of Science, Research and Arts.