Journal article

Interdependence of stroke outcome scales: reliable estimates from the Virtual International Stroke Trials Archive (VISTA)

FC Goldie, RL Fulton, B Frank, KR Lees

INTERNATIONAL JOURNAL OF STROKE | WILEY-BLACKWELL | Published : 2014

Abstract

BACKGROUND AND PURPOSE: Clinical deficits from stroke are diverse, prompting measurement in trials by a range of outcome scales. Statistical and clinical advantage can be gained by combining scales into a global outcome provided combinations are chosen with limited correlations. We aimed to clarify the interdependence of outcome scales by systematic review of published data and by novel analysis of data from completed acute trials. SUMMARY OF REVIEW: We systematically searched ScienceDirect and PubMed to summarize published data on correlations between stroke outcome scales. We generated new data on correlations among salient scales at 90 days poststroke in patients from the Virtual Internat..

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