Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

B Marshall; H Puthalakath; S Caria; S Chugh; M Doerflinger; PM Colman; M Kvansakul

Journal article

Variola virus F1L is a Bcl-2-like protein that unlike its vaccinia virus counterpart inhibits apoptosis independent of Bim

B Marshall, H Puthalakath, S Caria, S Chugh, M Doerflinger, PM Colman, M Kvansakul

Cell Death & Disease | NATURE PUBLISHING GROUP | Published : 2015

DOI: 10.1038/cddis.2015.52

University of Melbourne Researchers

Marcel Doerflinger Author Medical Biology (W.E.H.I.)

Peter Colman Author Medical Biology (W.E.H.I.)

Grants

Awarded by National Health and Medical Research Council Australia

Awarded by Australian Research Council

Funding Acknowledgements

We thank A Wardak for technical assistance; staff at the Australian Synchrotron for assistance with diffraction data collection; CSIRO C3 Centre for assistance with crystallization. This work was supported by the National Health and Medical Research Council Australia (Project Grant APP1007918 and Fellowship 637372 to MK, Fellowship and Program Grant to PMC), Australian Research Council (Fellowship FT130101349 to MK), the Cooperative Research Center for Biomarker Translation (scholarship to BM), the Victorian State Government Operational Infrastructure Support and the Australian Government NHMRC IRIISS. Data deposition: Coordinates for F1L were deposited with the Protein Data Bank, accession code 5ajj and 5ajk.