Aberrant actin depolymerization triggers the pyrin inflammasome and autoinflammatory disease that is dependent on IL-18, not IL-1 beta
Man Lyang Kim, Jae Jin Chae, Yong Hwan Park, Dominic De Nardo, Roslynn A Stirzaker, Hyun-Ja Ko, Hazel Tye, Louise Cengia, Ladina DiRago, Donald Metcalf, Andrew W Roberts, Daniel L Kastner, Andrew M Lew, Dena Lyras, Benjamin T Kile, Ben A Croker, Seth L Masters
Journal of Experimental Medicine | ROCKEFELLER UNIV PRESS | Published : 2015
Awarded by National Institutes of Health
Awarded by National Health and Medical Research Council
This work was supported by project grants (1008131 and 1043414), program grants (1016647 and 1037321), fellowships (to B.T. Kile, B.A. Croker, A.M. Lew, and S.L. Masters), a National Institutes of Health grant (1R56AI103352-01A1; to B.A. Croker), and an Independent Research Institutes Infrastructure Support Scheme grant (361646) from the National Health and Medical Research Council; fellowships from the Victorian Endowment for Science Knowledge and Innovation (to S.L. Masters), the Australian Research Council (to B.A. Croker and B.T. Kile), the Sylvia and Charles Viertel Charitable Foundation (to B.T. Kile), and the Cancer Council of Victoria (to D. Metcalf); the Australian Cancer Research Foundation, the Australian Phenomics Network, and a Victorian State Government Operational Infrastructure Support grant.