Journal article

Case report of a p16(INK4A)-positive branchial cleft cyst

T McLean, C Iseli, D Amott, M Taylor

JOURNAL OF LARYNGOLOGY AND OTOLOGY | CAMBRIDGE UNIV PRESS | Published : 2015

Abstract

OBJECTIVE: To report the occurrence of a concurrent oropharyngeal papilloma and branchial cleft cyst linked by p16(INK4A) and human papillomavirus immunohistochemistry. CASE REPORT: A 42-year-old woman presented with a 1-month history of a left lateral neck mass. Contrast enhanced computed tomography showed a hypodense lesion 20 mm in diameter anteromedial to the left sternocleidomastoid muscle. Ultrasound-guided fine needle aspiration suggested a branchial cleft cyst. Panendoscopy was performed at the time of neck mass removal, and a papillomatous lesion was removed from the left hypopharynx. Histopathological analysis showed the neck lesion to be a branchial cyst containing lymphoid tissue..

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