Quality of Life Following Repair of Large Hiatal Hernia is Improved but not Influenced by Use of Mesh: Results From a Randomized Controlled Trial
Jan H Koetje, Tanya Irvine, Sarah K Thompson, Peter G Devitt, Simon D Woods, Ahmad Aly, Glyn G Jamieson, David I Watson
World Journal of Surgery | SPRINGER | Published : 2015
INTRODUCTION: Laparoscopic surgery is the treatment of choice for repair of large hiatus hernia, but can be followed by recurrence. Repair with prosthetic mesh has been recommended to prevent recurrence, although complications following mesh repair have generated disagreement about whether or not mesh should be used. The early objective and clinical results of a randomized trial of repair with mesh versus sutures have been reported, and revealed few differences. In the current study, we evaluated quality of life outcomes within this trial at follow-up to 2 years. METHODS: In a multicenter prospective double-blind randomized trial three methods for repair of large hiatus hernia were compared:..View full abstract
Awarded by National Health and Medical Research Council (NHMRC) of Australia
This randomized trial was supported by Research Project Grants from the National Health and Medical Research Council (NHMRC) of Australia-Grant numbers 375111 and 1022722. We are grateful for the assistance of Ms Lorelle Smith, Ms Nicky Carney and Ms Lorraine Sheehan-Hennessy who contributed to data collection, and Drs Susan Gan and Philip Game who helped with enrolment of patients into the randomized trial. This trial is registered with the Australia and New Zealand Clinical Trials Registry ACTRN12605000725662.