Control of Trachoma in Australia: A Model Based Evaluation of Current Interventions
Andrew J Shattock, Manoj Gambhir, Hugh R Taylor, Carleigh S Cowling, John M Kaldor, David P Wilson
PLOS NEGLECTED TROPICAL DISEASES | PUBLIC LIBRARY SCIENCE | Published : 2015
BACKGROUND: Australia is the only high-income country in which endemic trachoma persists. In response, the Australian Government has recently invested heavily towards the nationwide control of the disease. METHODOLOGY/PRINCIPAL FINDINGS: A novel simulation model was developed to reflect the trachoma epidemic in Australian Aboriginal communities. The model, which incorporates demographic, migration, mixing, and biological heterogeneities, was used to evaluate recent intervention measures against counterfactual past scenarios, and also to assess the potential impact of a series of hypothesized future intervention measures relative to the current national strategy and intensity. The model simul..View full abstract
This study was funded by the Australian Government Department of Health and Ageing with the intention of using the work to inform best practice towards elimination by 2020. Representatives from the Australian Government reviewed the manuscript and provided comments for consideration. The study was also supported by the Australian Research Council and the National Health and Medical Research Council. The Kirby Institute is funded by the Australian Government, Department of Health and Ageing. The views expressed in this publication do not necessarily represent the position of the Australian Government. The Kirby Institute is affiliated with the University of New South Wales.