Journal article

Vigorous physical activity and carotid distensibility in young and mid-aged adults

Quan L Huynh, Christopher L Blizzard, Olli Raitakari, James E Sharman, Costan G Magnussen, Terence Dwyer, Markus Juonala, Mika Kahonen, Alison J Venn

Hypertension Research | NATURE PUBLISHING GROUP | Published : 2015


Although physical activity (PA) improves arterial distensibility, it is unclear which type of activity is most beneficial. We aimed to examine the association of different types of PA with carotid distensibility (CD) and the mechanisms involved. Data included 4503 Australians and Finns aged 26-45 years. Physical activity was measured by pedometers and was self-reported. CD was measured using ultrasound. Other measurements included resting heart rate (RHR), cardiorespiratory fitness (CRF), blood pressure, biomarkers and anthropometry. Steps/day were correlated with RHR (Australian men r = -0.10, women r = - 0.14; Finnish men r = -0.15, women r = -0.11; P<0.01), CRF and biochemical markers, bu..

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Funding Acknowledgements

We gratefully acknowledge the contributions of all CDAH and Young Finns staff and volunteers, and the participants. The CDAH study was funded by grants from the Australian National Health and Medical Research Council, the Australian National Heart Foundation, the Tasmanian Community Fund and Veolia Environmental Services. We gratefully thank the CDAH study sponsors (Sanitarium Health Food Company, ASICS Oceania and Target Australia). The Young Finns study was funded by the Academy of Finland, the Social Insurance Institution of Finland, Turku University Foundation, Juho Vainio Foundation, Finnish Foundation of Cardiovascular Research, Tampere University Hospital, and the Finnish Cultural Foundation. Authors CLB, JES, CGM and AJV were supported by fellowships from the Australian National Health and Medical Research Council.