Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin
Beeke Wienert, Alister PW Funnell, Laura J Norton, Richard CM Pearson, Lorna E Wilkinson-White, Krystal Lester, Jim Vadolas, Matthew H Porteus, Jacqueline M Matthews, Kate GR Quinlan, Merlin Crossley
Nature Communications | NATURE PUBLISHING GROUP | Published : 2015
We thank Dale Wright from the Children's Hospital at Westmead for the karyotyping of K562 cells. We also thank Christopher Brownlee from BRIL (Flow Cytometry Facility, Mark Wainwright Analytical Centre) for his help and advice with flow cytometry and cell sorting. We thank the Ramaciotti Centre for Genomics for the Fluidigm Services. This work is supported by funding from the Australian National Health and Medical Research Council, and the Australian Research Council.