Journal article

Intervals to Plasmodium falciparum recurrence after anti-malarial treatment in pregnancy: a longitudinal prospective cohort

Natthapon Laochan, Sophie G Zaloumis, Mallika Imwong, Usa Lek-Uthai, Alan Brockman, Kanlaya Sriprawat, Jacher Wiladphaingern, Nicholas J White, Francois Nosten, Rose McGready

MALARIA JOURNAL | BMC | Published : 2015

Abstract

BACKGROUND: Plasmodium falciparum infections adversely affect pregnancy. Anti-malarial treatment failure is common. The objective of this study was to examine the duration of persistent parasite carriage following anti-malarial treatment in pregnancy. METHODS: The data presented here are a collation from previous studies carried out since 1994 in the Shoklo Malaria Research Unit (SMRU) on the Thailand-Myanmar border and performed using the same unique methodology detailed in the Materials and Methods section. Screening for malaria by microscopy is a routine part of weekly antenatal care (ANC) visits and therapeutic responses to anti-malarials were assessed in P. falciparum malaria cases. Wom..

View full abstract

Grants

Funding Acknowledgements

We sincerely thank the pregnant women who followed the antenatal clinics and agreed to finger-prick sampling. The work would not have been possible without the combined efforts of the midwives, medics, laboratory, and logistical teams. Julie A Simpson provided welcome statistical advice. This research was part of the Wellcome Trust Mahidol University Oxford Tropical Medicine Research Programme, supported by the Wellcome Trust of Great Britain (Major Overseas Programme-Thailand Unit Core Grant).