Journal article

How to best measure the effectiveness of male human papillomavirus vaccine programmes?

SM Garland, EG Molesworth, DA Machalek, AM Cornall, Sepehr N Tabrizi

CLINICAL MICROBIOLOGY AND INFECTION | ELSEVIER SCI LTD | Published : 2015

Abstract

In many countries now, vaccination of young adolescent girls with prophylactic human papillomavirus (HPV) vaccines has been rolled out as a public health programme. In countries where coverage has been high, this has led to dramatic reductions in cervical high-grade precancerous lesions, as well as genital warts. A reduction in circulating vaccine-related HPV types has also been demonstrated. With the introduction of gender-neutral approaches incorporating universal vaccination of pre-adolescent boys in some countries, implementation of post-vaccine monitoring will be critical to evaluate the incremental impact of male vaccination. In contrast to cervical screening programmes, population-wid..

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