Journal article

Quality of life: An important outcome measure in a trial of very early mobilisation after stroke

Karen Tyedin, Toby B Cumming, Julie Bernhardt



Purpose. Commencing an early and active mobilisation programme in the acute stages of stroke may have important physical and psychological benefits that might improve long-term quality of life. We hypothesised that patients who received very early mobilisation (VEM) would experience better quality of life than those receiving standard care (SC). Methods. The study was a Phase II single-blind randomised controlled trial: VEM patients received earlier (within 24 h of stroke onset) and more intensive physical therapy than SC patients for the first 14 days (or until discharge). Quality of life was measured using the Assessment of Quality of Life (AQoL) questionnaire, administered face-to-face by..

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Awarded by National Heart Foundation of Australia

Awarded by National Health and Medical Research Council (Australia)

Funding Acknowledgements

We would like to thank all participating patients and clinicians at the Austin hospital and St. Vincent's hospital and all the staff at the National Stroke Research Institute for their support and contributions, particularly Dorcas Quah (who conducted all blinded assessments) and Dr. Marcus Nicol. Thanks to Dr. Leonid Churilov for his valuable statistical assistance. The phase II trial was supported by grants from the National Heart Foundation of Australia (grant number G 04M 1571), Affinity Health, and an equipment grant from the Austin Health Medical Research Fund. Dr Bernhardt was supported by a National Health and Medical Research Council (Australia) fellowship (157305).