Journal article

The NIH Stroke Scale Can Establish Cognitive Function after Stroke

Toby B Cumming, Christian Blomstrand, Julie Bernhardt, Thomas Linden



BACKGROUND: Cognitive impairment is an important but underrecognised consequence of stroke. We investigated whether a subset of items from the NIH Stroke Scale (NIHSS) could yield valid information on cognitive status in a group of stroke patients. METHODS: 149 stroke patients from the Göteborg 70+ Stroke Study were investigated after 18 months. We extracted 4 items corresponding to the NIHSS items on orientation, executive function, language and inattention. Scores on this subset of 4 NIHSS items (Cog-4) and the Mini-Mental State Examination (MMSE) were evaluated against a reference diagnosis of severe cognitive impairment. RESULTS: The area under the receiver-operator curve (AUC) plotted f..

View full abstract


Awarded by Swedish Medical Research Council

Awarded by Swedish ALF/LUA

Funding Acknowledgements

The authors would like to thank Elisabeth Cid-Daun, Ann-Catrin Muhl, Valter Sundh and Erica Torstensson for their technical assistance with the project. This study was supported by grants from the Swedish Brain Research Foundation, the Yngve Lands Memorial Foundation, the John and Brit Wennerstrom Foundation for Neurological Research, the Amlov Foundation, the Swedish Stroke Association Research Foundation, Per Olof Ahl's Foundation for Cerebrovascular Research, the King Gustaf V and Queen Victoria Foundation, the Swedish Medical Research Council Grant No. 11337 and the Swedish ALF/LUA Research Grant ALFGBG-11364.