Journal article
Factors associated with transmission of influenza-like illness in a cohort of households containing multiple children
CR Brown, JM Mccaw, EJ Fairmaid, LE Brown, K Leder, M Sinclair, J Mcvernon
Influenza and Other Respiratory Viruses | WILEY | Published : 2015
DOI: 10.1111/irv.12331
Abstract
Background: Household studies of influenza-like illness (ILI) afford opportunities to study determinants of respiratory virus transmission. Objectives: We examined predictors of ILI transmission within households containing at least two children. Methods: A prospective cohort study recorded ILI symptoms daily for 2712 adult and child participants during the 1998 influenza season in Victoria, Australia. Logistic and Poisson regressions were used to explore predictors of household transmission of ILI and the secondary household attack proportion (SHAP). A date of illness onset during the influenza season was used as a proxy indicator of ILI associated with influenza infection (as opposed to ot..
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Funding Acknowledgements
We would like to acknowledge Professor Margaret Hellard of the Burnet Institute for initiating this study, by sharing data and specimens from her historical cohort. James McCaw is supported by an ARC Future Fellowship. Jodie McVernon is supported by an NHMRC Career Development Fellowship. We thank Steven Rockman from bioCSL for provision of the purified influenza virus.