T cells recognizing a 11mer influenza peptide complexed to H-2D(b) show promiscuity for peptide length
Damien Zanker, Kylie Quinn, Jason Waithman, Roleen Lata, Roger Murphy, Nicole Louise La Gruta, Weisan Chen
Immunology & Cell Biology | WILEY | Published : 2015
Awarded by NHMRC
This project was partly supported by the NHMRC project grants 433608, Program grant 567122. WC is an NHMRC Senior Research Fellow 603104; JW is supported by an NHMRC Postdoctoral fellowship and DZ was supported by an NHMRC Biomedical Postgraduate scholarship. We thank Drs Jonathan Yewdell and Jack Bennink (NIAID, NIH, Bethesda, MD, USA) for providing rVVs encoding individual IAV proteins and the anti-H-2D<SUP>b</SUP> B22.249 ascites; Dr Van Kaer (Department of Microbiology and Immunology, Vanderbilt University, Nashville, TN, USA) for providing LMP2<SUP>-/-</SUP> mice. Note: Amino acid position in the defined minimal T cell epitopes are subscripted, such as NP<INF>366-374</INF>; and all non-defined peptides or combined peptide regions are shown as normal text in brackets, such as PB2(198-207).