Journal article
Retinal Vessel Tortuosity and Its Relation to Traditional and Novel Vascular Risk Markers in Persons with Diabetes
MB Sasongko, TY Wong, TT Nguyen, CY Cheung, JE Shaw, R Kawasaki, EL Lamoureux, JJ Wang
Current Eye Research | TAYLOR & FRANCIS INC | Published : 2016
Abstract
Purpose/Aim: To investigate the association between retinal vascular tortuosity and traditional- and vascular-related risk factors in persons with diabetes. Methods: We recruited 224 diabetic patients. Retinal vascular tortuosity was measured from fundus photographs. Association of tortuosity with the following factors was assessed after adjusting for significant co-factors: diabetes duration, HbA1c, systolic blood pressure (SBP), cholesterol and body mass index (BMI), flicker-light induced retinal vasodilatation, and markers of endothelial function and inflammation (skin microvacular responses to acetylcholine iontophoresis, soluble e-selectin, inter-cellular adhesion molecule-1, vascular c..
View full abstractGrants
Awarded by Japan Society for the Promotion of Science
Funding Acknowledgements
None of the authors has potential conflicts of interest relevant to this article to disclose. CERA receives Operational Infrastructure Support from the Victorian Government. This study was supported by a Diabetes Australia Research Trust Grant (to J.J.W., T.Y.W, J.S. and T.T.N.) and by the National Health and Medical Research Council Centre for Clinical Research Excellence #529923 - Translational Clinical Research in Major Eye Diseases.