Journal article

Hypertensive Diseases of Pregnancy Predict Parent-Reported Difficult Temperament in Infancy

Monique Robinson, Wendy H Oddy, Andrew JO Whitehouse, Craig E Pennell, Garth E Kendall, Neil J McLean, Peter Jacoby, Stephen R Zubrick, Fiona J Stanley, John P Newnham



OBJECTIVE: Recent research has linked hypertensive diseases of pregnancy with adverse neurodevelopmental outcomes in childhood and adulthood. This study aimed to establish whether such effects are observed in infancy. METHODS: This was a prospective pregnancy cohort study of 2,785 pregnancies with complete data on hypertensive diseases of pregnancy. Mothers completed a validated Australian adaptation of the Toddler Temperament Scale when the children were 1 year of age (n = 2,384). Algorithms were used to classify children as difficult, slow to warm up, intermediate high, intermediate low, or easy, on the basis of their temperament scores. We then grouped difficult and intermediate-high infa..

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Awarded by National Health and Medical Research Council of Australia (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

Supported via core funding from the Raine Medical Research Foundation; The University of Western Australia (UWA); the Telethon Institute for Child Health Research; the UWA Faculty of Medicine, Dentistry and Health Science; the Women and Infants Research Foundation; and Curtin University. The Raine Study is also funded by the National Health and Medical Research Council of Australia (NHMRC; Grants #963209, #211912, #003209 and #353514), Australian Health Management, the Telstra Foundation, the Western Australian Health Promotion Foundation, the National Heart Foundation of Australia, and Beyond Blue. Dr M. Robinson is funded for this research by Australian Rotary Health. Prof A.J.O. Whitehouse is supported by an NHMRC Career Development Fellowship (#1004065). The authors declare no conflict of interest.