Regional Heterogeneity in the Configuration of the Intracortical Canals of the Femoral Shaft
Egon Perilli, Yohann Bala, Roger Zebaze, Karen J Reynolds, Ego Seeman
CALCIFIED TISSUE INTERNATIONAL | SPRINGER | Published : 2015
Three-dimensional (3D) characterization of cortical porosity, most of which is under 100 µm in diameter, is usually confined to measurements made in 3-4 mm diameter cylinders of bone. We used micro-computed tomography (micro-CT) scanning of entire transaxial cross sections of human proximal femoral shafts (30-35 mm diameter) to quantify regional variation in porosity within the same scan. Complete, up to 10-mm-thick, transaxial slices of femoral upper shafts from 8 female cadavers were studied (n = 3 aged 29-37 years, n = 5 aged 72-90 years). Scanning was performed using high-resolution micro-CT (8.65 µm/voxel). Micro-CT volumes (10 × 10 × 5 mm) were selected via software in the anterior, me..View full abstract
Funding for this study was provided by Osteoporosis Australia/Australia New Zealand Bone and Mineral Society, Amgen-GSK Grants Program 2012.