Genomic analysis of diversity, population structure, virulence, and antimicrobial resistance in Klebsiella pneumoniae, an urgent threat to public health
Kathryn E Holt, Heiman Wertheim, Ruth N Zadoks, Stephen Baker, Chris A Whitehouse, David Dance, Adam Jenney, Thomas R Connor, Li Yang Hsu, Juliette Severin, Sylvain Brisse, Hanwei Cao, Jonathan Wilksch, Claire Gorrie, Mark B Schultz, David J Edwards, Van Nguyen Kinh, Vu Nguyen Trung, Tuyet Dao Trinh, Martijn Mensinke Show all
Proceedings of the National Academy of Sciences | NATL ACAD SCIENCES | Published : 2015
Awarded by National Health and Medical Research Council of Australia
Awarded by Wellcome Trust
Awarded by Victorian Life Sciences Computation Initiative Grant
We thank the sequencing teams at the Wellcome Trust Sanger Institute (WTSI) for genome sequencing; Dr. Rattanaphone Phetsouvanh and the directors of Mahosot Hospital (Vientiane, Lao People's Democratic Republic) and Joy Silisouk for performing DNA extractions on the Lao strains; Associate Professor Tse Hsien Koh for isolates from the Singapore General Hospital (Singapore); T. Williammee and D. Sentochnik (Basett Healthcare) for human isolates from the United States; K. W. Simpson and B. Dogan (Cornell University) for isolates from human intestinal biopsies; and Brenda Werner and other staff at Quality Milk Production Services (Cornell University) for help in collecting and processing bovine and human samples from the United States. This work was funded by National Health and Medical Research Council of Australia Fellowships 628930 and 1061409 (to K. E. H.) and Program Grant 606788 (to R. A. S.); Wellcome Trust Grants 098051 (to the WTSI) and 089275/H/09/Z (to the Lao-Oxford-Mahosot Hospital-Wellcome Trust Research Unit); Sir Henry Dale Fellowship (cofunded by the Royal Society) (to S. Baker); and by Victorian Life Sciences Computation Initiative Grant VR0082.