Journal article

Temporal distribution of arrhythmic events in chronic kidney disease: Highest incidence in the long interdialytic period

Michael CG Wong, Jonathan M Kalman, Eugenia Pedagogos, Nigel Toussaint, Jitendra K Vohra, Paul B Sparks, Prashanthan Sanders, Peter M Kistler, Karen Halloran, Geoffrey Lee, Stephen A Joseph, Joseph B Morton

HEART RHYTHM | ELSEVIER SCIENCE INC | Published : 2015

Abstract

BACKGROUND: Chronic kidney disease (CKD) patients undergoing hemodialysis (HD) have a high risk of sudden cardiac death (SCD). A unique risk factor may be a longer interval between HD sessions (interdialytic period). Inherent in conventional HD (thrice-weekly) are two 48-hour short breaks (SIDP) and one 72-hour long break (LIDP) between HD sessions. OBJECTIVE: We used an implantable cardiac monitor (ICM) to define the incidence and timing of significant arrhythmias in an HD population. METHODS: Fifty CKD patients undergoing HD with left ventricular ejection fraction >35% had an ICM inserted, with intensive follow-up to record SCD events and predefined bradyarrhythmias and tachyarrhythmias. R..

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