Temporal distribution of arrhythmic events in chronic kidney disease: Highest incidence in the long interdialytic period
Michael CG Wong, Jonathan M Kalman, Eugenia Pedagogos, Nigel Toussaint, Jitendra K Vohra, Paul B Sparks, Prashanthan Sanders, Peter M Kistler, Karen Halloran, Geoffrey Lee, Stephen A Joseph, Joseph B Morton
HEART RHYTHM | ELSEVIER SCIENCE INC | Published : 2015
BACKGROUND: Chronic kidney disease (CKD) patients undergoing hemodialysis (HD) have a high risk of sudden cardiac death (SCD). A unique risk factor may be a longer interval between HD sessions (interdialytic period). Inherent in conventional HD (thrice-weekly) are two 48-hour short breaks (SIDP) and one 72-hour long break (LIDP) between HD sessions. OBJECTIVE: We used an implantable cardiac monitor (ICM) to define the incidence and timing of significant arrhythmias in an HD population. METHODS: Fifty CKD patients undergoing HD with left ventricular ejection fraction >35% had an ICM inserted, with intensive follow-up to record SCD events and predefined bradyarrhythmias and tachyarrhythmias. R..View full abstract
Awarded by Keith Goldsbury Postgraduate Research Scholarship Award from the National Heart Foundation of Australia
This study was made possible by a research grant from St Jude Medical. Dr. Wong is the recipient of the Keith Goldsbury Postgraduate Research Scholarship Award (ID: PC11M 6218) from the National Heart Foundation of Australia.