Postprandial Responses to Lipid and Carbohydrate Ingestion in Repeated Subcutaneous Adipose Tissue Biopsies in Healthy Adults
Aimee L Dordevic, Felicity J Pendergast, Han Morgan, Silas Villas-Boas, Marissa K Caldow, Amy E Larsen, Andrew J Sinclair, David Cameron-Smith
Nutrients | MDPI | Published : 2015
Adipose tissue is a primary site of meta-inflammation. Diet composition influences adipose tissue metabolism and a single meal can drive an inflammatory response in postprandial period. This study aimed to examine the effect lipid and carbohydrate ingestion compared with a non-caloric placebo on adipose tissue response. Thirty-three healthy adults (age 24.5 ± 3.3 year (mean ± standard deviation (SD)); body mass index (BMI) 24.1 ± 3.2 kg/m2, were randomised into one of three parallel beverage groups; placebo (water), carbohydrate (maltodextrin) or lipid (dairy-cream). Subcutaneous, abdominal adipose tissue biopsies and serum samples were collected prior to (0 h), as well as 2 h and 4 h after ..View full abstract
Funding was received from the Molecular & Medical Research Strategic Research Centre and the School of Exercise & Nutrition Sciences, Deakin University and the Liggins Institute, University of Auckland. The authors would like to acknowledge Andrew Garnham for performing the adipose tissue biopsy procedure and Paul Della Gatta for assistance with performing the Bioplex serum analysis.