Tobacco smoking and hand eczema - Is there an association?

Abstract

Background Numerous risk factors have been suggested for hand eczema. This systematic review evaluates the association between tobacco smoking and hand eczema. Objective To review the literature systematically on the association between smoking and hand eczema. Methods The PubMed and EMBASE databases were searched up to 27 January 2015 for articles on the association between tobacco smoking and hand eczema, including human studies in English and German only. Experimental studies, studies on tobacco allergy, case reports, reviews and studies on second-hand smoking were excluded. Results Twenty articles were included. Among studies in occupational settings, three of seven found a statistically..