Donor Recruitment for Fecal Microbiota Transplantation
Sudarshan Paramsothy, Thomas J Borody, Enmoore Lin, Sarah Finlayson, Alissa J Walsh, Douglas Samuel, Johan van den Bogaerde, Rupert WL Leong, Susan Connor, Watson Ng, Hazel M Mitchell, Nadeem Kaakoush, Michael A Kamm
Inflammatory Bowel Diseases | LIPPINCOTT WILLIAMS & WILKINS | Published : 2015
BACKGROUND: Increasing demand for fecal microbiota transplantation (FMT) has created a need for stool banks sourced from long-term healthy donors. Here, we describe our experience in recruiting and screening fecal donors. METHODS: Mailbox, newspaper, and online advertisements were used. Potential donors were required to satisfy a prescreen telephone conversation, pass blood and stool investigations, then undertake a screening interview including medical history, physical examination, and evaluation of donor selection criteria. RESULTS: One hundred sixteen potential donors were prescreened of whom 74 failed-47 declined based on study donation requirements (primarily related to frequency and d..View full abstract
The clinical trial (ClinicalTrials.govIdentifier: NCT01896635) upon which this manuscript is based has received funding from the Broad Medical Research Program at CCFA and the GESA IBD Clinical Research Grant.