Journal article

OS074. Brachial artery flow-mediated dilatation as a predictor of pre-eclampsia in the first trimester of pregnancy.

JA Gurgel Alves, SP Brennecke, F da Silva Costa

Pregnancy Hypertens | Published : 2012

Abstract

INTRODUCTION: Increased vascular reactivity secondary to endothelial injury has been reported to be involved in the pathogenesis of pre-eclampsia (PE). However, whether these observations of vascular activity are the result or the cause of PE is still not fully understood. Some studies have shown that pregnant women who subsequently suffer from PE have an impaired flow-mediated dilatation in the brachial artery at the beginning of the second half of pregnancy. However this parameter has not been tested as a first trimester predictor of PE. OBJECTIVES: To investigate the role of maternal brachial artery reactivity during the first trimester of pregnancy (11-14 weeks) for the prediction of PE...

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