Journal article

Evolution of Endovascular Therapy in Acute Stroke: Implications of Device Development

Adithya Balasubramaian, Peter Mitchell, Richard Dowling, Bernard Yan

Journal of stroke | KOREAN STROKE SOC | Published : 2015


Intravenous thrombolysis is an effective treatment for acute ischaemic stroke. However, vascular recanalization rates remain poor especially in the setting of large artery occlusion. On the other hand, endovascular intra-arterial therapy addresses this issue with superior recanalization rates compared with intravenous thrombolysis. Although previous randomized controlled studies of intra-arterial therapy failed to demonstrate superiority, the failings may be attributed to a combination of inferior intra-arterial devices and suboptimal selection criteria. The recent results of several randomized controlled trials have demonstrated significantly improved outcomes, underpinning the advantage of..

View full abstract