Analysing cardiac autonomic neuropathy in diabetes using electrocardiogram derived systolic-diastolic interval interactions

Abstract

Systole and diastole are the fundamental periods of the cardiac cycle and their relative duration is used to evaluate heart function in various physiological and pathological conditions. In clinical practice, systolicdiastolic interval is generally measured using echocardiography. However, recent studies have shown that the QT and TQ intervals of the electrocardiogram (ECG) signal can be used as surrogate systolic and diastolic intervals respectively and the ratio of beat-tobeat QT-TQ intervals can be used as the systolic-diastolic interval interaction (SDI) parameter. In this study, we propose a new parameter, beat-to-beat TQ-RR ratio, to investigate the SDI. Performance of both QT-TQ and T..