A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis

Ben J Gu; Judith Field; Sebastien Dutertre; Amber Ou; Trevor J Kilpatrick; Jeannette Lechner-Scott; Rodney Scott; Rodney Lea; Bruce V Taylor; Jim Stankovich; Helmut Butzkueven; Melissa Gresle; Simon M Laws; Steven Petrou; Sabine Hoffjan; Denis A Akkad; Colin A Graham; Stanley Hawkins; Anna Glaser; Sahl Khalid Bedri; Jan Hillert; Carlos Matute; Alfredo Antiguedad; James S Wiley

Journal article

A rare P2X7 variant Arg307Gln with absent pore formation function protects against neuroinflammation in multiple sclerosis

Ben J Gu, Judith Field, Sebastien Dutertre, Amber Ou, Trevor J Kilpatrick, Jeannette Lechner-Scott, Rodney Scott, Rodney Lea, Bruce V Taylor, Jim Stankovich, Helmut Butzkueven, Melissa Gresle, Simon M Laws, Steven Petrou, Sabine Hoffjan, Denis A Akkad, Colin A Graham, Stanley Hawkins, Anna Glaser, Sahl Khalid Bedri Show all

Human Molecular Genetics | OXFORD UNIV PRESS | Published : 2015

DOI: 10.1093/hmg/ddv278

University of Melbourne Researchers

Steven Petrou Author Florey Department of Neuroscience and Mental Health

James Wiley Author Florey Department of Neuroscience and Mental Health

Trevor Kilpatrick Author Florey Department of Neuroscience and Mental Health

Judith Field Author Anatomy and Neuroscience

Ben Gu Author Florey Department of Neuroscience and Mental Health

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Grants

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

This work was supported by grants from the National Health and Medical Research Council of Australia (project grants 633275, 1048082) and the Victorian Government's Operational Infrastructure Support Program.