Journal article

Randomized controlled trial of probiotics after colonoscopy

Basil D'Souza, Timothy Slack, Shing W Wong, Francis Lam, Mark Muhlmann, Jakob Koestenbauer, Jonathan Dark, Graham Newstead

ANZ JOURNAL OF SURGERY | WILEY | Published : 2017

Abstract

BACKGROUND: Up to 20% of patients have ongoing abdominal symptoms at day 2 and beyond following colonoscopy. It was hypothesized that some of these symptoms are related to alterations in gut microbiota secondary to bowel preparation and would improve with probiotics compared with placebo. METHODS: Patients were given either a probiotic or placebo capsule in the days following colonoscopy. Colonoscopy was performed with air insufflation. The probiotic capsule contained the strains Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07. Patients recorded their symptoms at 1 h, 1, 2, 4, 7 and 14 days post colonoscopy and returned results once their symptoms had resolved. The primary ou..

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University of Melbourne Researchers