Childhood maltreatment and transition to psychotic disorder independently predict long-term functioning in young people at ultra-high risk for psychosis

AR Yung; J Cotter; SJ Wood; P McGorry; AD Thompson; B Nelson; A Lin

Journal article

Childhood maltreatment and transition to psychotic disorder independently predict long-term functioning in young people at ultra-high risk for psychosis

AR Yung, J Cotter, SJ Wood, P McGorry, AD Thompson, B Nelson, A Lin

PSYCHOLOGICAL MEDICINE | CAMBRIDGE UNIV PRESS | Published : 2015

DOI: 10.1017/S003329171500135X

Abstract

BACKGROUND: Individuals identified as at ultra-high risk (UHR) for psychosis are at risk of poor functional outcome regardless of development of psychotic disorder. Studies examining longitudinal predictors of poor functioning have tended to be small and report only medium-term follow-up data. We sought to examine clinical predictors of functional outcome in a long-term longitudinal study. METHOD: Participants were 268 (152 females, 116 males) individuals identified as UHR 2-14 years previously. A range of clinical and sociodemographic variables were assessed at baseline. Functioning at follow-up was assessed using the Social and Occupational Functioning Assessment Scale (SOFAS). RESULTS: Ba..

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University of Melbourne Researchers

Stephen Wood Author Centre for Youth Mental Health

Andrew Thompson Author Centre for Youth Mental Health

Patrick McGorry Author Centre for Youth Mental Health

Barnaby Nelson Author Centre for Youth Mental Health

Alison Yung Author Centre for Youth Mental Health

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Grants

Awarded by National Health and Medical Research Council (NHMRC)

Awarded by NHMRC

Funding Acknowledgements

This work was supported by National Health and Medical Research Council (NHMRC) programme grants (350241 and 566529) to A.R.Y., S.J.W. and P.M., the Colonial Foundation, and an unrestricted research grant from Janssen-Cilag. A.R.Y., S.J.W. and B.N. were supported by NHMRC Awards and B.N. by a Griffith Fellowship. A.L. is currently supported by an NHMRC Award (no. 1072593). No funding source played any role in the collection, analysis, interpretation, or publication of data.