Journal article

A Prospective Ultrasound Study of Prenatal Growth in Infant Siblings of Children With Autism

Lisa M Unwin, Murray T Maybery, Anthony Murphy, Wendy Lilje, Michelle Bellesini, Anna M Hunt, Joanna Granich, Peter Jacoby, Cheryl Dissanayake, Craig E Pennell, Martha Hickey, Andrew JO Whitehouse

AUTISM RESEARCH | WILEY | Published : 2016


Numerous studies have observed that a proportion of infants later diagnosed with autism spectrum disorder (ASD) experience accelerated head growth during the first years of life. An emerging methodology for examining the developmental trajectory prior to a diagnosis of ASD is to investigate siblings of affected individuals. The current study is the first prospective investigation of fetal growth in siblings of children with ASD. Two groups of pregnant women were recruited as part of the PRegnancy Investigation of Siblings and Mothers of children with autism cohort in Perth, Western Australia. The "high risk" group (n = 23) comprised pregnant women who have an existing child with a diagnosis ..

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Awarded by National Health and Medical Research Council

Funding Acknowledgements

This research was funded by a Project Grant (APP1003424) and Senior Research Fellowship to AJOW (APP1077966) from the National Health and Medical Research Council. The authors would like to acknowledge Western Ultrasound for Women for their contribution to procuring the ultrasound scans, and the participating families who generously donated their time to this study. Unwin, Maybery, Murphy, Lilje, Bellesini, Hunt, Granich, Jacoby, Dissanayake, Pennell, Hickey, and Whitehouse report no biomedical financial interests or potential conflicts of interest.