Does rumination mediate the relationship between mindfulness and depressive relapse?

Abstract

Objectives Major depressive disorder is a significant mental illness that is highly likely to recur, particularly after three or more previous episodes. Increased mindfulness and decreased rumination have both been associated with decreased depressive relapse. The aim of this study was to investigate whether rumination mediates the relationship between mindfulness and depressive relapse. Design This prospective design involved a secondary data analysis for identifying causal mechanisms using mediation analysis. Methods This study was embedded in a pragmatic randomized controlled trial of mindfulness-based cognitive therapy (MBCT) in which 203 participants (165 females, 38 males; mean age: 48..