Journal article

Focal seizure symptoms in idiopathic generalized epilepsies

Udaya Seneviratne, Jia J Woo, Ray C Boston, Mark Cook, Wendyl D'Souza



OBJECTIVE: We sought to study the frequency and prognostic value of focal seizure symptoms (FSS) in idiopathic generalized epilepsies (IGE) using a validated tool: Epilepsy Diagnostic Interview Questionnaire and Partial Seizure Symptom Definitions. METHODS: Participants with IGE were recruited from epilepsy clinics at 2 tertiary hospitals. The diagnosis was validated and classified into syndromes according to the International League Against Epilepsy criteria by 2 epileptologists independently with discordance resolved by consensus. The Epilepsy Diagnostic Interview Questionnaire utilizes both open- and closed-ended questions to elicit FSS in association with generalized tonic-clonic seizure..

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Funding Acknowledgements

U. Seneviratne has received travel and speaker honoraria from UCB Pharma. J. Woo and R. Boston report no disclosures relevant to the manuscript. M. Cook has received speaker honoraria from UCB Pharma and Sanofi Australia and travel honoraria from UCB Pharma and SciGen. He has received research grants from National Health and Medical Research Council (Australia) and Australian Research Council. He has also received a Science, Technology, and Innovation Grant from the State Government of Victoria, Australia. W. D'Souza has received travel, investigator-initiated, and speaker honoraria from UCB Pharma, educational grants from Novartis Pharmaceuticals and Pfizer Pharmaceuticals, educational, travel, and fellowship grants from GSK Neurology Australia, and honoraria from SciGen Pharmaceuticals. Go to for full disclosures.