Stress Responses of Small Heat Shock Protein Genes in Lepidoptera Point to Limited Conservation of Function across Phylogeny
Bo Zhang, Jincheng Zheng, Yu Peng, Xiaoxia Liu, Ary A Hoffmann, Chun-Sen Ma
PLoS One | PUBLIC LIBRARY SCIENCE | Published : 2015
The small heat shock protein (sHsp) family is thought to play an important role in protein refolding and signal transduction, and thereby protect organisms from stress. However little is known about sHsp function and conservation across phylogenies. In the current study, we provide a comprehensive assessment of small Hsp genes and their stress responses in the oriental fruit moth (OFM), Grapholita molesta. Fourteen small heat shock proteins of OFM clustered with related Hsps in other Lepidoptera despite a high level of variability among them, and in contrast to the highly conserved Hsp11.1. The only known lepidopteran sHsp ortholog (Hsp21.3) was consistently unaffected under thermal stress i..View full abstract
Awarded by National Special Fund for Agro-scientific Research in the Public Interest
Awarded by Beijing Natural Science Foundation
This research was supported by the National Special Fund for Agro-scientific Research in the Public Interest (No. 201103024) and Beijing Natural Science Foundation (5144032). CSM and BZ are the authors who received the fundings respectively. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.