Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5

Indu R Chandrashekaran; Biswaranjan Mohanty; Edmond M Linossi; Laura F Dagley; Eleanor WW Leung; James M Murphy; Jeffrey J Babon; Sandra E Nicholson; Raymond S Norton

Journal article

Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5

Indu R Chandrashekaran, Biswaranjan Mohanty, Edmond M Linossi, Laura F Dagley, Eleanor WW Leung, James M Murphy, Jeffrey J Babon, Sandra E Nicholson, Raymond S Norton

Biochemistry | AMER CHEMICAL SOC | Published : 2015

DOI: 10.1021/acs.biochem.5b00619

University of Melbourne Researchers

Edmond Linossi Author Medical Biology (W.E.H.I.)

Laura Dagley Author Medical Biology (W.E.H.I.)

James Murphy Author Medical Biology (W.E.H.I.)

Jeffrey Babon Author Medical Biology (W.E.H.I.)

Sandra Nicholson Author Medical Biology (W.E.H.I.)

Grants

Awarded by National Health and Medical Research Council (NHMRC), Australia

Awarded by NHMRC TRUSS Grant

Awarded by Cancer Council Victoria Grant

Funding Acknowledgements

This work was supported in part by the National Health and Medical Research Council (NHMRC), Australia (Program Grant 1016647), as well as an NHMRC TRUSS Grant 361646, a Cancer Council Victoria Grant 1065180 and a Victorian State Government Operational Infrastructure Scheme grant. E.M.L was supported by an Australian Postgraduate Award. R.S.N. acknowledges fellowship support from the NHMRC. J.M.M. and J.J.B acknowledge fellowship support from the Australian Research Council.