Journal article
The Oxygen-Mediated Synthesis of 1,3-Butadiynes in Continuous Flow: Using Teflon AF-2400 to Effect Gas/Liquid Contact
Trine P Petersen, Anastasios Polyzos, Matthew O'Brien, Trond Ulven, Ian R Baxendale, Steven V Ley
CHEMSUSCHEM | WILEY-V C H VERLAG GMBH | Published : 2012
Abstract
The gas is always greener: A continuous flow Glaser-Hay coupling reaction system, mediated by molecular oxygen, is developed based on a tube-in-tube gas/liquid reactor/injector. The system uses a semi-permeable Teflon AF-2400 membrane to effect rapid gas/liquid contact in flow, affording homogeneous solutions of oxygen. Measurements of out-gassing downstream of the back-pressure regulator indicate the onset of saturation is reached after about 16 seconds. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Grants
Awarded by BP
Awarded by Engineering and Physical Sciences Research Council
Funding Acknowledgements
We thank the following institutions for financial support: The Danish Agency for Science, Technology and Innovation and H. Lundbeck A/S (T.P.P.), CSIRO Material Science and Engineering (A.P.), EPSRC (M.O'B.), the BP 1702 Professorship (S.V.L.), and The Royal Society (I.R.B.).