Journal article

Ultrasonography in the intensive care setting can be used to detect changes in the quality and quantity of muscle and is related to muscle strength and function

Selina M Parry, Doa El-Ansary, Michael S Cartwright, Aarti Sarwal, Sue Berney, Rene Koopman, Raquel Annoni, Zudin Puthucheary, Ian R Gordon, Peter E Morris, Linda Denehy



PURPOSE: This study aimed to (1) document patterns of quadriceps muscle wasting in the first 10 days of admission and (2) determine the relationship between muscle ultrasonography and volitional measures. MATERIALS AND METHODS: Twenty-two adults ventilated for more than 48 hours were included. Sequential quadriceps ultrasound images were obtained over the first 10 days and at awakening and intensive care unit (ICU) discharge. Muscle strength and function were assessed at awakening and ICU discharge. RESULTS: A total of 416 images were analyzed. There was a 30% reduction in vastus intermedius (VI) thickness, rectus femoris (RF) thickness, and cross-sectional area within 10 days of admission. ..

View full abstract


Awarded by National Health and Medical Research Council Dora Lush Scholarship

Funding Acknowledgements

This research has been undertaken by SP (primary author) as part of her doctoral qualification with the support of the National Health and Medical Research Council Dora Lush Scholarship (103923). Author RK is currently in receipt of a CR Roper Fellowship, and author SB is a recipient of a National Health and Medical Research Council Fellowship. Authors RK, SB, and LD are in receipt of National Health and Medical Research Council project grants. None of the funding bodies and fellowships were involved or influenced the design or publication of this study. On behalf of all authors, the corresponding author states that there is no conflict of interest.