Strong ion and weak acid analysis in severe preeclampsia: potential clinical significance
CM Ortner, B Combrinck, S Allie, D Story, R Landau, K Cain, RA Dyer
BRITISH JOURNAL OF ANAESTHESIA | ELSEVIER SCI LTD | Published : 2015
BACKGROUND: The influence of common disturbances seen in preeclampsia, such as changes in strong ions and weak acids (particularly albumin) on acid-base status, has not been fully elucidated. The aims of this study were to provide a comprehensive acid-base analysis in severe preeclampsia and to identify potential new biological predictors of disease severity. METHODS: Fifty women with severe preeclampsia, 25 healthy non-pregnant- and 46 healthy pregnant controls (26-40 weeks' gestation), were enrolled in this prospective case-control study. Acid-base analysis was performed by applying the physicochemical approach of Stewart and Gilfix. RESULTS: Mean [sd] base excess was similar in preeclampt..View full abstract
Awarded by Institute of Translational Health Sciences, Seattle, WA 98109
This work was supported by the Institute of Translational Health Sciences, Seattle, WA 98109 (ITHS: 63-5503 (XX3CZU)).