pilot study to compare dry cervical sample collection with standard practice of wet cervical samples for human papillomavirus testing
Farhana Sultana, Dorota M Gertig, C David Wrede, Dallas R English, Julie A Simpson, Kelly T Drennan, Julia ML Brotherton, Gillian Phillips, Stella Heley, Philip E Castle, Marion Saville
JOURNAL OF CLINICAL VIROLOGY | ELSEVIER SCIENCE BV | Published : 2015
BACKGROUND: For human papillomavirus (HPV) DNA detection, specimen collection and transportation using a dry swab without transport medium has advantages, in various situations, over liquid media. OBJECTIVE: In this pilot study we evaluated whether a dry cervical sample taken with a flocked swab (dry sample) is a valid alternative for HPV DNA testing compared with the standard practice of a wet sample taken with a cyto-broom placed directly into liquid media (wet sample). STUDY DESIGN: Women attending the dysplasia clinic at the Royal Women's Hospital, Melbourne Australia between November 2013 and February 2014 were enrolled. During colposcopic examination, a practitioner collected wet and d..View full abstract
F.S. is supported by the Endeavour Postgraduate Scholarships and Fellowships sponsored by the Australian Government, Department of Education and Training. We thank Barbara McBride, Nurse Coordinator, Amy Cooper, Clinical Nurse Specialist and all the other staff at the Dysplasia clinic for their support during the period of data collection. We also thank the VCS Pathology staff for processing and testing the samples. We also acknowledge all participating women.