The microbiome of otitis media with effusion in Indigenous Australian children

J Jervis-Bardy; GB Rogers; PS Morris; HC Smith-Vaughan; E Nosworthy; LEX Leong; RJ Smith; LS Weyrich; J De Haan; AS Carney; AJ Leach; S O'Leary; RL Marsh

Journal article

The microbiome of otitis media with effusion in Indigenous Australian children

J Jervis-Bardy, GB Rogers, PS Morris, HC Smith-Vaughan, E Nosworthy, LEX Leong, RJ Smith, LS Weyrich, J De Haan, AS Carney, AJ Leach, S O'Leary, RL Marsh

International Journal of Pediatric Otorhinolaryngology | Published : 2015

DOI: 10.1016/j.ijporl.2015.07.013

Abstract

Introduction: Indigenous Australian children have a high prevalence of otitis media with effusion (OME) and associated conductive hearing loss. Only three microbiological studies of middle ear fluid (MEF) from Indigenous Australian children with OME have been reported. All of these were reliant on culture or species-specific PCR assays. The aim of this study was to characterise the middle ear fluid (MEF), adenoid and nasopharyngeal (NP) microbiomes of Indigenous Australian children, using culture-independent 16S rRNA gene sequencing. Methods: MEF, NP swabs and adenoid specimens were collected from 11 children in the Alice Springs region of Central Australia. Bacterial communities in these sp..

View full abstract

University of Melbourne Researchers

Stephen O'Leary Author

Related Projects (2)

SURGERY FOR THE TREATMENT OF OTITIS MEDIA IN INDIGENOUS AUSTRALIAN CHILDREN

Ear infection (otitis media) is a major problem amongst children living in remote Australian communities. Medical treatment often fails, and..

IMPROVING SURGICAL TECHNIQUE FOR RELIABLE LONG-TERM HEARING OUTCOMES IN INDIGENOUS CHILDREN WITH CHRONIC OTITIS MEDIA

The overwhelming burden of otitis media (middle ear inflammation, OM) and the consequences of hearing loss on social and educational outcome..

Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This study was supported by the National Health and Medical Research Council of Australia (Project Grant 1007641; Fellowships 1024175 to HCSV, 1020561 to AJL, 1034703 to RLM; and the Centre for Research Excellence Grant 1078557).