Journal article
Effect of Vitamin D supplementation on selected inflammatory biomarkers in older adults: A secondary analysis of data from a randomised, placebo-controlled trial
M Waterhouse, B Tran, PR Ebeling, DR English, RM Lucas, AJ Venn, PM Webb, DC Whiteman, RE Neale
British Journal of Nutrition | Published : 2015
Abstract
Observational studies have suggested that 25-hydroxyvitamin D (25(OH)D) levels are associated with inflammatory markers. Most trials reporting significant associations between vitamin D intake and inflammatory markers used specific patient groups. Thus, we aimed to determine the effect of supplementary vitamin D using secondary data from a population-based, randomised, placebo-controlled, double-blind trial (Pilot D-Health trial 2010/0423). Participants were 60- to 84-year-old residents of one of the four eastern states of Australia. They were randomly selected from the electoral roll and were randomised to one of three trial arms: placebo (n 214), 750 μg (n 215) or 1500 μg (n 215) vitamin D..
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Funding Acknowledgements
[ "This project was funded by the National Health and Medical Research Council (NHMRC) of Australia (grant no. 613655). P. M. W., R. E. N., A. J. V., R. M. L. and D. C. W. are supported by Fellowships from the National Health and Medical Research Council. The investigational product was supplied free of charge by Sanofi-Aventis Healthcare Pty Ltd trading as Sanofi Consumer Healthcare, Virginia, QLD, Australia.", "P. R. E. has received prior funding from Sanofi-Aventis Healthcare. All other authors have no conflicts of interest to disclose." ]