Journal article

The influence of rate of stimulation and pulse duration on efficacy of deep brain stimulation for Essential Tremor

CM McKay, HJ McDermott, T Perera, R Peppard, M Jones, AP Vogel

Brain Stimulation | Elsevier | Published : 2015


Deep brain stimulation (DBS) is used to alleviate tremor in patients diagnosed with Essential Tremor who do not respond to conventional treatments. To achieve optimal tremor suppression, a large stimulus parameter space needs to be explored. In practice, a default pulse duration and stimulation rate (generally 60 us and 130 Hz) are often chosen and current or voltage varied to determine a clinically effective setting. This study explored the effect of rate of stimulation in 5 patients with bilateral DBS stimulation to the posterior sub-thalamic area (PSA). Additionally, the effects of varying charge per pulse by varying pulse duration alone or by varying current/voltage alone were compared. ..

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