Journal article

Contrasted patterns in mating-type chromosomes in fungi: Hotspots versus coldspots of recombination

Alexander Idnurm, Michael E Hood, Hanna Johannesson, Tatiana Giraud

FUNGAL BIOLOGY REVIEWS | ELSEVIER SCI LTD | Published : 2015

Abstract

It is striking that, while central to sexual reproduction, the genomic regions determining sex or mating-types are often characterized by suppressed recombination that leads to a decrease in the efficiency of selection, shelters genetic load, and inevitably contributes to their genic degeneration. Research on model and lesser-explored fungi has revealed similarities in recombination suppression of the genomic regions involved in mating compatibility across eukaryotes, but fungi also provide opposite examples of enhanced recombination in the genomic regions that determine their mating types. These contrasted patterns of genetic recombination (sensu lato, including gene conversion and ectopic ..

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University of Melbourne Researchers

Grants

Awarded by US National Science Foundation


Awarded by National Institutes of Health


Awarded by Fungi-Sex


Awarded by ERC


Awarded by NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES


Funding Acknowledgements

Our research has been supported by the US National Science Foundation grants DEB-1115765 and DEB-0747222, National Institutes of Health grant R21 AI094364, the Australian Research Council, the Swedish Research Council, the Fungi-Sex ANR-09-0064-01 grant, and the ERC starting grant GenomeFun 309403.